Stephen J Freedland教授:肥胖可导致前列腺癌的发生

Published at: 2015年第1卷第S1期


编者按:2017年12月9日-10日,由中国抗癌协会泌尿男生殖系统肿瘤专业委员会、上海市抗癌协会联合主办,复旦大学附属肿瘤医院承办的中国抗癌协会泌尿男生殖系统肿瘤专委会2017年会暨第七届上海泌尿肿瘤国际论坛在上海隆重举行。本次大会邀请到了国内顶尖泌尿科专家,及多家国际知名肿瘤中心专家与会,针对各自的专业领域作了专题报告,并且对国内外最新技术和热点研究进行分享讲授和解疑答惑。借此机会,我们很荣幸邀请到本次参会嘉宾,美国MD Anderson癌症中心Run Wang教授针对阴茎假体植入、干细胞疗法、微能量疗法等勃起功能障碍的治疗方法表达了自己的看法(图1)。

图1. AME出版社科学编辑与Run Wang教授合影

人物聚焦:Run Wang

Run Wang, MD, FACS.

Dr. Run Wang is the Professor of Surgery(Urology)and Cecil M. Crigler, MD Chair in Urology at the University of Texas Medical School at Houston, Texas, USA. He is also the Professor of Urology and Director of Sexual Medicine in the Department of Urology at the University of Texas MD Anderson Cancer Center. He is the secretary general for the World Chinese Urological Society and the President-elect for the Sexual Medicine Society of North America.

Dr. Wang’s research interests are male sexual function, benign prostate hyperplasia, and erectile dysfunction as a result of prostate cancer treatment, penile rehabilitation and male infertility. His current basic research activities include stem cell gene therapy with nanotechnology for erectile dysfunction after radical prostatectomy and vacuum therapy for Peyronie’s disease in animal model.

Dr. Wang has authored 126 articles and chapters in peer-reviewed journals and books. He served as a panelist for WHO sponsored Consultations in Sexual Medicine in 2009 and is selected to be a member in 2015.


目前,阴茎假体植入被认为是一些重度勃起功能障碍患者的三线疗法。Wang教授认为,阴茎假体植入是重度勃起功能障碍最有效的治疗手段。由于药物治疗、物理治疗、负压治疗等治疗方法无效,或由于禁忌症而不能服用药物,阴茎假体植入手术是许多勃起功能障碍患者的一线疗法,虽然标准上被认为是三线疗法。同时Wang教授认为,三件式可膨胀性阴茎假体是目前最先进的假体之一。这种可膨胀性假体一共分为三部分,包括两根空心圆柱、一个贮液囊和一个泵。这样的假体和手术方式基本上都能满足夫妇双方的需求,术后患者的满意度很高。同时阴茎假体保持时间长,不需要定期更换。Wang教授指出, 在他的患者当中,有些患者接受假体植入术已经20年,阴茎假体仍在使用。


干细胞研究已经成为当今生命科学的前沿和热点。 Wang教授认为,尽管目前有很多关于勃起功能障碍的干细胞治疗研究,但我们并不了解这些基础研究,研究尚不成熟,在应用这种治疗方法前,需要更多的临床试验和随机对照试验。关于微能量疗法治疗勃起功能障碍, Wang教授表示个人目前不会选择这种治疗方法,微能量疗法目前缺乏好的临床试验,关于需要做哪些治疗、在何处起作用、需要关注哪些地方,治疗频率等没有一个标准的衡量,因此仍需要做大量的研究,未来可适用于轻度勃起功能障碍的患者的治疗。




1. Currently, penile prosthesis implantation is considered the third line treatment option for some severe erectile dysfunction (ED) patients, and they have been reported to be a successful treatment with a high patient and partner satisfaction rate. We would like to know which is the most advanced penile prosthesis today, and how long can they be used and whether they need to be replaced regularly?

2. Penile prosthesis has been applied for treating patients with severe ED, but this method may be far from the perfect, such as higher cost, complications, and high requirements of physician. Could you share with us the new progress or the possible new technique in the future for the treatment of severe ED?

3. As we know, stem cell therapy for ED has made great progress in the basic research field, how do you feel about the prospect of this treatment?

4. Of recent years, scientists follow awfully with interest of the microenergy medicine for the treatment of ED. What is your opinion about the potential effect of low-energy shock wave therapry or low-intensity pulsed ultrasound therapy for ED treatment?

5. We have confusion about the relationship between the cavernous nerve and dorsal nerve. Could you briefly introduce the differences between them? Why does the injury of the cavernous nerve affect the dorsal nerve?

6. Would you like to share with us any stories that keep you going and being an urologist? What encourage you to choose it as your career?

采访编辑:徐文珂,AME Publishing Company

撰写编辑:伍艳清,AME Publishing Company

视频编辑:麦雪芳,AME Publishing Company

责任编辑:许梦杨,AME Publishing Company



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